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Horizon Spectra

Built to reveal the biology behind every tumor

Somatic interpretation of tumors that goes beyond variants in isolation characterizing total mutation burden for deeper insight into diagnosis and treatment.

Bringing clarity to cancer genetics

Cancer genetics, decoded as a whole. Horizon Spectra looks beyond isolated variants, characterizing the full somatic mutation landscape of 26 malignant cancer types to reveal tumor biology, drug response, and progression as one coherent picture.

AMP Tiers

Horizon implements Association for Molecular Pathology (AMP) somatic tiers across 26 types of malignant cancers, fully compatible with short and long-read, surfacing variant pathogenicity and standard-of-care insight with FDA-approved drugs, plus additional classification tiers for diagnostic and therapeutic insight.

AMP Tiers

SeqRx

Horizon SeqRx connects genomic findings to therapeutic decisions, pairing somatic variant calls with treatment guidance at the point of care. It dynamically cross-references patient-specific mutations against a vast repository of FDA-approved targeted therapies and actively recruiting global clinical trials.

Pharmacogenomics and Clinical Trial Database
Why Spectra

Precision at every tier

A clinical-grade interpretation layer for oncologists, pathologists, and translational research programs working across the pan-cancer spectrum.

AMP-Tiered Classification
Every somatic variant tiered against AMP guidelines across 26 malignant cancer types, long read compatible, with FDA-approved drug matches.
Therapy Linkage
Somatic variant calls linked directly to treatment guidance for faster, better-informed decisions.
Tumor Mutation Burden
Collective somatic mutation burden surfaces tumor progression, drug options, and prognostic indicators.
Mutation Signatures
Computed tumor signatures reveal the tumor's underlying biological processes, long read compatible and targeted therapy options.
Clonal Complexity
Clonal structure visualized across the tumor's somatic mutations to reveal evolution, resistance, long read compatible and subclone progression.
Built for Tertiary Analysis
Starts directly from called variants VCF for SNVs, and a dedicated format for structural variants straight into AMP-tiered sign-out.
Supported Technologies

One platform, every sequencing scale

Spectra scales across sequencing modalities and specimen types, from whole genome sequencing through targeted liquid biopsy.

Long Read WGS & Exome

Comprehensive somatic and germline coverage across the whole genome or exome for the fullest view of tumor biology.

Long read WGS and exome coverage
Get Started

Outpace tumor evolution one variant at a time

Bring Spectra into your oncology program and shorten every tumor board decision.

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