For a variant to be functionally relevant it must impact both the mRNA and the protein. Horizon delivers multimodal insight from patient-derived transcriptomics, proteomics, and phenotypes read together.
Horizon Multimodal brings together genomic, transcriptomic, proteomic, and phenotypic signals in a single workflow. For a variant to be functionally relevant it must impact both the mRNA and the protein not a single assay read in isolation.
Gene-level expression across different cell types is critical information for tumors and other genetic conditions. Horizon visualises single-cell expression so a transcript signal can be traced back to the cell type where it actually matters.
The functional relevance of a variant can be estimated by integrating patient-derived proteomics confirming that a transcript-level signal actually carries through to the protein.
To predict the gene relevant to a set of complex phenotypes, Horizon enables integration of unstructured phenotypes through an LLM, read alongside the transcript and protein layers, not in isolation.
Horizon unifies transcript, protein, and phenotype into a single functional read-out so a candidate variant is scored on whether its effect actually propagates through the biology, not on one assay alone.
A real, ordered workflow three steps from raw patient data to a functional read on every candidate variant.
Bring patient-derived transcriptomics and proteomics. Sample IDs stay in a single, auditable table.
Transcript, protein, and unstructured phenotype are aligned into one functional model per gene.
Read which variants are functionally relevant, with the cell types and evidence layers behind each call.
Bring us a case we'll interpret it with you, end-to-end.
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